Nifedipine-Induced Gingival Hypertrophy

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Nifedipine-induced gingival hypertrophy.

A 55-year-old man was referred to us because of renal dysfunction (serum creatinine 1.82 mg/dL). Three years earlier, he had aortic dissection associated with left renal artery occlusion and had undergone surgery for ascending aorta and aortic arch replacement. He had been receiving the following medications for 3 years; nifedipine (Adalat-CR) 40 mg, carvedilol 10 mg, aspirin 100 mg, allopurino...

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Nonsurgical Management of Nifedipine Induced Gingival Overgrowth

Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosp...

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Amlodipine-induced massive gingival hypertrophy.

EDITOR’S KEY POINTS • Amlodipine is commonly prescribed in family practice for hypertension. Gingival hypertrophy is an often overlooked but potentially harmful side effect of treatment with amlodipine and other calcium channel blockers. • The patient in the case presented had gingival hypertrophy as a result of managing his hypertension with amlodipine; the problem completely resolved when he ...

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Gingival hyperplasia with nifedipine.

36 Hind CR, Winearls CG, Lockwood CM, Rees AJ, Pepys MB. Objective monitoring of activity in Wegener's granulomatosis by protein concentration. Clin Nephrol 1984; 21:341-5. 37 Imbach P. Wegener'sche granulomatose. Ergeb Inn Med Kinderheilkd 1977;39:33-54. 38 Lehmann H, Neidermayer W. Stadienteilung der Wegener'schen granulomatose. Med Welt 1987;38: 466-9. 39 Lehmann H, Keifer B. Clinical manife...

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Therapy for nifedipine-induced gingival overgrowth by saireito in rats

OBJECTIVE A calcium antagonist, nifedipine, causes gingival overgrowth as a side effect. It has been confirmed that the Japanese traditional medicine, Saireito, inhibits the nifedipine-induced proliferation of gingival fibroblasts in vitro. We performed an in vivo experiment to determine whether Saireito has a therapeutic use in the treatment of nifedipine-induced gingival overgrowth. METHODS...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2012

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.51.6626